Dusting off iconic text books for @MScGenomicsNcl today

Databases? who needs those when you have the following……….

Text books

Novum Organum by Sir France Bacon (1620)

An Atlas of General Affections of the skeleton by Sir Thomas Fairbank (1951)

Heritable Disorders of Connective Tissue by Victor McKusick (3rd Edition 1966)

Bone Dysplasias by Spranger, Brill & Poznanski (2nd Edition 2002)

Connective Tissue and its Heritable Disorders by Royce and Steinman (2nd Edition 2002)

Genomics of Common and Rare Genetic Disease @MScGenomicsNcl

Study Day 2 of GNM8003 Genomics of Common and Rare Genetic Disease

Institute of Genetic Medicine, Newcastle University

MSc coursebanner

The exciting programme is as follows……programme

Proteaosome, proteaosome, wherefore art though proteaosome…..

Pete has recently returned from a quick trip to Professor Massimo Coletta’s lab in Rome to investigate the pathological interplay between the proteasome and matrilin-3 mutations.

He was working with Diego Sbardella and Grazia Raffaella Tundo to help refine disease mechanisms in genetic skeletal dysplasias.

And many thanks to both.

So here we have a quick poem for that visit……..

Proteasome, proteasome, wherefore art though proteasome?

Study they expression and define thy function; for if thou wilt not degrade mutant matrilin-3, wilt though consider COMP?

Shall I over express thee or shall I knock thee down? tis but an experiment that I should do………..

[The alternative William Shakespeare]

Pete, Deigo, Grazia

Pete, Diego and GraziaHard at work

….and hard at work