Pete has recently returned from a quick trip to Professor Massimo Coletta’s lab in Rome to investigate the pathological interplay between the proteasome and matrilin-3 mutations.
He was working with Diego Sbardella and Grazia Raffaella Tundo to help refine disease mechanisms in genetic skeletal dysplasias.
And many thanks to both.
So here we have a quick poem for that visit……..
Proteasome, proteasome, wherefore art though proteasome?
Study they expression and define thy function; for if thou wilt not degrade mutant matrilin-3, wilt though consider COMP?
Shall I over express thee or shall I knock thee down? tis but an experiment that I should do………..
[The alternative William Shakespeare]