Targeted mouse models of recessive spondyloepimetaphyeal dysplasia, aggrecan type
Why Make Mouse Models of the Aggrecanopathies?
Because cell model studies to date have provided no links between aggrecan mutations and disease mechanisms…….
Image from ANIMAL INSIDE OUT: A BODY WORLDS Production at the International Centre for Life in Newcastle
I'm saying 'adolescent' because the growth plate has not fused (like a mouse), but is that true for a lion....?